Motor Fluctuation

Variations in motor function experienced by people with Parkinson's Disease, typically related to medication timing. During 'on' periods when medication is working optimally, motor symptoms are controlled; during 'off' periods as medication wears off, symptoms like tremor, rigidity, and slowness return or worsen. Fluctuations become more pronounced as PD progresses. For accessibility, motor fluctuations mean a person's abilities can change significantly throughout the day—they may be able to use a standard interface during on periods but require full accessibility accommodations during off periods. This variability challenges assumptions about static disability profiles.